| Name | Gender | Meaning | Favorites |
| Sabari | Boy | God Ayyappan | |
| Sabarinathan | Boy | Lord Ayyapa | |
| Sadhana | Girl | Devoted | |
| Sakthivel | Boy | Another name for God Murugan | |
| Saminathan | Boy | Lord murugan | |
| Sangeeta | Girl | Music, Musical | |
| Sarala | Girl | Honest, Straight | |
| Saravanan | Boy | Another name for God Murugan, Lord murugan | |
| Saravanavel | Boy | Another name for God Murugan | |
| Selvan | Boy | Prosperous | |
| Selvi | Girl | Youthful | |
| Sembaruthi | Girl | Hibiscus, Name of a Beautiful Flower | |
| Semmal | Boy | Perfect | |
| Senbagam | Girl | Name of a Beautiful Flower | |
| Sendhil | Boy | Lord murugan | |
| Sendhilkumaran | Boy | God Murugan | |
| SendhilNathan | Boy | Lord murugan | |
| Shivani | Girl | Goddess Parvati | |
| Silambarasan | Boy | The best | |
| Siva | Boy | God Sivan | |
